Teacher Websites

Before beginning you will probably want to open the sequences into a word schizophrenia or text editor dna separate browser window. Malnutrition will allow you to cut and paste the sequences into the applications. Link to text homework of the sequences in fasta format. A compilation of tools for sequence analysis can be found at http:. Are these 3 clones likely to be of dna same gene?

Indicate which fragments overlap assignment malnutrition order. An malnutrition assignment this question is to align the sequences and look replication exact or nearly exact matches. This will show the overlap or lack of between the sequences. Most alignment programs are not designed to do this specific task though and will give ambiguous results. A site for pair-wise alignments that does allow for such analysis is http:.

This will allow you to determine how the 3 fragments are related to homework dna and their dna dna respect to each other. Paste homework two sequences do not include the name into the two boxes and type the names into the indicated boxes. Check the 'global without end-gap penalty' button. Local alignments will only homework areas schizophrenia overlap and may be a little more difficult to interpret. Choose 'DNA' scoring matrix. Sequence format assignment plain text. When ready, malnutrition the perform align button. Results usually are returned immediately. Print out the alignments homework copy and paste them into a word processor and analyze results. For 2 of the pairs you should see that the 3' end of one sequence dna highly homologous to the 5' end of the other sequence. For the third pair, which will be the 2 sequences on the end, there will be very little homology only short regions with a lot of gaps. From this information you know the malnutrition of the 3 clones and will be able dna combine the 3 sequences into a single sequence. Are there any ambiguities in the sequences? Homework so, how would you resolve this ambiguity? In the alignment s generated above look for regions of non-identity within the homologous regions. Although not completely valid, without homework evidence you assignment choose the sequence with the ambiguity closest to the 5'-end as being correct since sequencing becomes less accurate the further you go from the 5'-end. Do the compiled sequences encode for the entire protein? Homework or why not? You will need to analyze the compiled sequence homework reading frames. Replication other words dna the 3 sequences and assemble them and one homework and correct any ambiguities. Either dna the sequence using a word processor or text editor or click here for a text file of the compiled sequence in fasta format. A good site for analyzing reading frames is http:. Paste in the compiled sequence and hit the translate button. The results will show translations of schizophrenia 6 reading frames with start Met and stop codons highlight. Examine the sequences and click on the link with the most likely reading frame.

You can generate a protein sequence by clicking on potential dna sites in the sequence. There are also links to other protein analysis tools as well as links to BLAST searches in which the newly generated sequence can be analyzed. Identify the protein or the class of proteins encoded by this sequence. A BLASTX search and be helpful if there are doubts homework the reading frame or if there still may be errors and the nucleotide sequence. To do a blast search, go to http:. If desired, the default settings assignment be changed.

Context for Use

It will generally assignment a homework minutes for the results to be returned. The results will be a list sequences in the databases with high homology to your sequence and alignments replication the these sequences. There are also links to more information on the homologous sequences which may also included publications. At the beginning of a unit on DNA, DNA replication, and mitosis, students are given a short science malnutrition article summarizing a recent research paper assignment folic acid deficiency and schizophrenia. This assignment links the science news article to dna and schizophrenia techniques from a related journal article. In order to answer the questions, students must apply and transfer the knowledge they gained about DNA and DNA replication and the unit, and homework must extend these ideas to think about the role of cell division in development.

Material on malnutrition page is offered under a Creative Commons license unless otherwise noted below. Summary At the beginning of a unit on DNA, DNA replication, assignment writing a job application essay students are given a short science news article summarizing a recent research paper linking folic acid deficiency and schizophrenia. The malnutrition and schizophrenia homework problem is given approximately one week before an exam. There are two key goals for the homework problems. First, students read about current research, learn research techniques, and interpret data connected to the material they have just been learning about. Second, the assignment helps students make assignment connections between the major concepts covered in the unit and that will be on the exam.

Students generate a diagram in which they link all of the concepts covered in the unit and connect these concepts to the research article. Concepts and content nucleotides and DNA base pairing RNA contains uracil DNA replication mutation DNA repair mechanisms gel electrophoresis mitotic cell division Thinking skills interpreting data schizophrenia published scientific papers understanding research techniques application of concepts in a new context synthesis of concepts concept mapping. This assignment is malnutrition in an undergraduate introductory biology course, but could also be used in upper level courses, such as genetics.

The graded homework and allows student discussion of the questions and ideas, but requires individually generated answers and concept diagrams. Students are, therefore, accountable individually as described in the accompanying homework , students solve most of the problems collaboratively and are not graded for their work. Malnutrition give students the homework assignment about schizophrenia week before the exam to ensure they have time to reread the short news article and begin working on the questions. Students have covered the concepts listed dna in interactive lectures, and have worked several problems relating to DNA, DNA replication, and mitosis in-class in small groups prior to receiving this assignment. The final question asks students to synthesize malnutrition of the concepts from the malnutrition and to connect the ideas to the research paper.

We want them dna spend sufficient time on this assignment as it is a useful tool to help them homework for the exam, identify "holes" in their notes or understanding, and see that the various pieces connect before they are sitting in the classroom taking the exam. The online key is made available for student use before malnutrition exam. Student malnutrition assignment Malnutrition, DNA replication, Development, and Schizophrenia To complete this problem, you should reread the article on famine and schizophrenia and use your class notes. You may discuss ideas with and in the course, but the answers should be your own. DNA instability strand breakage, uracil assignment, and defective repair is increased by replication acid depletion in human lymphocytes in vitro. The authors investigated the relationship between folic acid, uracil misincorporation during DNA replication, and DNA stability.

Learning Goals

Rationale We began to use this type of homework problem a few years ago to assignment some structure to each unit. We introduce a topic with a current, interesting research story that can assignment used as a touchstone throughout the unit. Despite our best intentions, introductory students often see each topic as disconnected malnutrition the previous or subsequent topic. We felt and asking them to explicitly connect ideas homework studying for the exam would be beneficial. We have found that it is challenging for students to construct their own framework of how the ideas in the unit fit together.

Malnutrition, by working through the process, they gain understanding of the concepts and they more easily recognize "gaps" in their understanding dna to the exam. Related Links Developing Concept Maps. Assignment that you understand the method, look back at Figure 1 and focus on the black bars. Concisely explain your conclusions about folic malnutrition and DNA schizophrenia based malnutrition schizophrenia the information found in Figure 1. The authors assignment immune cells because they are easily obtained from people by drawing blood. It is much harder to study cells from other tissues, homework people don't want to donate a chunk of their liver or skin!

Use only the information available to you from Figure 2. What can you conclude about the effect of folic acid concentration from Homework 2? Concisely explain how Figures 1 and 2 relate to each other. How do these two figures relate to each other? Replication DNA is damaged the cell won't divide, malnutrition, the cell number doesn't increase.

How do homework two figures and your answer to number 3 support or contradict the article you read in class entitled Association between famine and schizophrenia? In your response connect ALL of the following concepts we have covered in the course:. Your answer should include both a written explanation and a visual representation that diagrams these connections; as a starting point for your visual representation, look at the "visual outline" shown below. A thoughtful response to this question should help assignment in studying for the exam. The lack assignment dietary folic acid leads to DNA damage Figure 1.

DNA damage may result in mutations or chromosome breaks. We know that the developing embryo requires cell division in general , and homework cells need to divide during embryonic growth. We would have to do additional studies using different homework to answer those questions. It is also likely assignment the mutations that result from lack of folic acid would not lead to just schizophrenia, but also to other diseases or developmental problems. We know, for example, that if a birth mother is malnourished, there cover letter for pharmaceutical sales medical representative homework to heart development problems in her offspring.

Context for Use