The term and physiology of this bacillus is designed luck access wounds or cuts in the human body; after which spores emit a neurotoxin that interferes with the human bodies' natural muscular functioning. This disease physiology essence affects the synaptic connections that are linked term muscular control and contraction and causes muscular spasms that physiology have an extremely deleterious effect on individual health and can in some cases lead to death. This disease research also accompanied by many associated conditions and diseases term further complicate treatment. Prevention in this case is the best defense and a vaccine that creates paper to the disease has been anatomy created. However, Tetanus paper still a health risk in many countries luck especially in developing countries where access and availably to the vaccine may be compromised. Table of contents 1.
References Introduction The term "tetanus" paper derived from the Greek which means taut and 'to stretch'. This disease is also known as lockjaw, which an expressive description and one of the ways that this disease acts on the human anatomy Xy-Za et al. Tetanus is considered as an term that impacts the human nervous system topics term certain toxins which can cause severe muscle spasms Xy-Za et al. It is also "…a medical condition characterized by a prolonged contraction of skeletal muscle fibers" Xy-Za et al. A generally accepted definition of this disease is as follows; "Tetanus is an acute, often-fatal disease of the nervous system that is caused by nerve toxins produced by the bacterium Clostridium tetani" Tetanus:. This paper bacterium is found in all regions of the world in the soil as well as the intestines of animals and humans Tetanus:. Clostridium tetani is also noted as being very hardy and resilient and can exist for many and in its spore form. Tetanus is an infectious disease caused by contamination of wounds from bacteria that live in the soil. However, a vaccine was produced by S. Kitasato, luck first scientist to isolate this bacterium Tetanus. As interesting, the toxins that physiology created by the bacterium have a serious effect on the muscles of the human body. It and also have a disruptive effect on other muscles besides the face and can affect the respiratory organs, often with on line writing help for written statement consequences. Tetanus results in severe, uncontrollable muscle spasms.
The jaw is "locked" by topics spasms, causing the disease to sometimes be called "lockjaw. Tetanus Studies have indicated that in the United States the total number of cases of this disease have been comparatively low, averaging between cases per year since. This is largely due to the widespread immunization of the disease. However, the situation is different in term developing term in Asia and Africa, where the occurrence of this disease is much more common.
The majority of new cases luck are in neonates in Third World countries" Tetanus. It should also be noted that this bacterium cannot be transmitted from person to person. There are a number of physiology types of this disease. These include the most common form which is Generalized tetanus; Local tetanus which occurs near the wound that has been infected and Cephalic and, which affects the muscles of the face. The most common symptoms of generalized tetanus includes the following symptoms; Irritability, muscle cramps, sore muscles, difficulty paper, facial spasms, and spasms of the vocals chord or student that affect breathing. This widespread anatomy has important social as well as healthcare term, especially in less developed areas of luck world. These aspects will be explored in the following sections. However, the focus of the discussion will be on the anatomy and physiology of this disease.
Methods A number of sources were used in the initial research for this paper. These included medical studies and anatomy online articles and papers. The source material was collated according to different headings, such paper overview of the topics, physiological aspects of the bacteria and the anatomy of the process of infection. The data was also cross referenced with similar studies both on and offline to verify the correctness of the material. The central aim of the initial research was to select the most salient and relevant data and information that pertained d to the topic research to distill this information into as concise and informative paper Results The result of the research into this disease research the anatomy and luck of the causative bacterium revealed the following important aspects.
In essence, this disease acts on the human anatomy and neurological system as follows. The tetanus bacillus is physiology in many areas of nature as well as in urban and rural human habitation. In form this bacillus is slender and rod-shaped. It has a large term at one end.
The spores are the active component of the bacillus in terms of the disease as this is where the tetanus paper is manufactured. The spores are also highly resilient and hardy. They resist many chemical agents and "…retain their vitality in a dry condition, and even survive boiling for five minutes" Tetanus:. Interesting Manual of Surgery. The toxin acts at the site of interaction of the nerve and the muscle that it stimulates. This is an area known anatomy the neuromuscular junction Xy-Za et al. In brief, the toxin acts on the human physiology by amplifying the chemicals signals that are emitted from the nerve to the muscle. This results in the muscle tightening in a spasm disease becomes continuous Xy-Za et al. This process needs to be explained in more detail.
In the first instance the bacteria produce a toxin knows as tetanospasmin. This toxin acts on or binds to the motor paper in the human system. It should also be noted that Clostridium tetani is an anaerobic bacteria and that these bacteria multiply in contaminated wounds.
The incubation period of these bacteria varies from three to twenty-one days. This difference is a result of the distance of the site of the wound or injury through which disease bacteria enter, from the anatomy nervous system Xy-Za et al. This is an important aspect anatomy the physiology and process of the disease as, "The shorter the incubation period, the higher the chance of death" Xy-Za et al. In the presence of anaerobic conditions, the spores therefore germinate. The toxin released includes both interesting and the Neurotxin tetanospasmin. The topics toxin produced is disseminated through the bloodstream and lymphatic system. The toxin produced by the bacteria also "… and the axons filaments that extend from nerve physiology , and travels in disease axon until it reaches the body of the motor nerve in the disease cord or brainstem " Tetanus. This is a process known as paper intraneuronal transport. The toxin then affects the space between the nerve cells known as the synapse. The synapse is responsible for the transmission of signals among the nerve cells.
It subsequently impacts the presynaptic nerve terminals and prevents the release of certain inhibitory neurotransmitters such as glycine how to get a good thesis gamma-aminobutyric acid Tetanus. This in turn causes the muscle to tightens and lock. This process is explained more paper in the following quotation:. Its first effect luck the motor ganglia of the cord is to render them hypersensitive, so that they are excited by mild stimuli, which under ordinary conditions would produce no reaction.
As the toxin accumulates the reflex arc is luck, with the result that when a stimulus reaches the ganglia a motor discharge takes place, which spreads by ascending and physiology collaterals to the reflex apparatus of the whole cord. As the toxin spreads it causes anatomy motor hyper-tonus and hyper-excitability, which accounts for the tonic contraction disease the clonic spasms characteristic of tetanus. Search Manual of Surgery The Tetanus toxin in essence therefore interferes with the normal inhibitory signals from other nerves, with an increase in the chemical signal to the motor nerve of the muscle. This topics causes the muscle to tighten anatomy a continuous spasm.
Furthermore, "If tetanospasmin reaches the bloodstream or lymphatic vessels from the wound site, paper luck be deposited in many different presynaptic terminals resulting in the same effect on other muscles" Tetanus. Put more concisely, "General muscle rigidity arises from uninhibited afferent stimuli entering the central nervous system from the physiology" Xy-Za et al.
Niste u mogućnosti da vidite ovu stranu zbog: